Simple one-pot regioselective 6-O-phosphorylation of carbohydrates and trehalose desymmetrization.
نویسندگان
چکیده
Biologically essential carbohydrate 6-phosphates, especially trehalose 6-phosphate, can be synthesized easily in excellent overall yields in 2 steps involving minimum protecting group manipulations. We can cleave the diphenylphosphate group for further synthetic objectives.
منابع مشابه
Iron(III) chloride-tandem catalysis for a one-pot regioselective protection of glycopyranosides.
Tandem catalysis by using iron(III) chloride hexahydrate leads to carbohydrate building blocks displaying an orthogonal protecting group pattern as illustrated by the regioselective protection of trehalose and maltose disaccharides.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 98 شماره
صفحات -
تاریخ انتشار 2013